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CHU Sainte-Justine
Centre de recherche
3175 Chemin de la Côte Sainte-Catherine
Montréal  (QC), Canada
H3T 1C5
514 345-4931 #5618
Career Summary, Research Topics and Interests


Pediatric surgeon with a 2-year specialization in Fetal Surgery (clinical and research)

Research Interests

Her research interests focus on in utero gene therapy, more specifically on immunological responses after presentation of viral vectors during the pre-immune period. Can a state of tolerance be introduced to these vectors that allow post-natal readministration? Dr Bouchard is also interested in the correction of metabolic diseases in transgenic mice through the antenatal administration of viral vectors. Other research areas on fetal surgery from a technical point of view are also to be developed on larger animal models.

Awards and Distinctions
  • Resident Award Winner, Eight Minute Presentation, American Academy of Pediatrics, Section on Surgery, 2000

  • Dean's List, University of Montreal, 2000

  • Medical Research Council of Canada Fellowship Award (now CIHR), 2000

  • Winner of the 1999 Resident Best Paper Award. Azzie G, Yazbeck S, Garel L, Dubois J, Bouchard S. Manual detorsion in cases of testicular torsion: A viable option

  • McLaughlin Scholarship for research training in fetal surgery, 1999

  • Scholarship for a presentation at the 3rd International Congress on Hepatic Transplantation, 1998

  • Award for Outstanding Resident Teaching, Department of Surgery, McGill University, 1996-1997

  • Lange Medical Publications Award for outstanding achievement as a medical student, 1992

  • Top 10% of the Preparatory Medicine class, 1988

Most Important Publications Selected by the Researcher
Bouron-Dal Soglio D, Rougemont A-L, de Buys Roessingh AS, Fetni R, Rypens FF, Bouchard S, Montpetit A, Fournet JC,
Chondroid cystic malformation of the lung with trisomy 8 mosaicism: a new cystic lung malformation
Am J Surg Pathol 2008  1095-1100.
Côté G, Bouchard S,
Hepatotoxicity after desflurane anesthesia in a 15-month-old child with Mobius syndrome after previous exposure to isoflurane
Anesthesiology 2007  843-845.
Bouchard S, Mackenzie TC, Radu AP, Hayashi S, Peranteau BH, Chirmule N, Flake AW,
Long-term transgene expression in cardiac and skeletal muscle following fetal administration of adenoviral or adeno-associated viral vectors in mice
J Gene Med 2003  941-950.
Davey MG, Hedrick HL, Bouchard S, Mendoza JM, Schwarz U, Adzick NS, Flake AW,
Temporary in utero tracheal occlusion in fetal sheep with severe lung hypoplasia does not restore postnatal respiratory function
J Appl Physiol 2003  1054-1062.
Mackenzie TC, Kobinger GP, Kootstra NA, Radu AP, Sena-Esteves M, Bouchard S, Wilson JM, Verma IM, Flake AW,
Efficient transduction of liver and muscle after in utero injection of lentiviral vectors with different pseudotypes
Mol Ther 2002  349-358.
Publications reported to FRSQ

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