• Assistant Clinical Professor, Allergy-Immunology-Rheumatology Unit, Department of Pediatrics, University of Montreal.

• Clinical Investigator, CHU Sainte-Justine Research Center.

Education

• PhD (Immunology), Pasteur Institute, Université Pierre et Marie Curie (UPMC), Paris, 2006-2010.

• Master’s (Immunology), Faculty of Medicine, Necker Hospital for Sick Children, UPMC, Paris, 2004-2005.

• Fellowship in Pediatric Immunology and Rheumatology, Necker Hospital for Sick Children, Paris, 2003-2005.

• Specialized Studies Diploma in Pediatrics, University of Montreal, 1999-2003.

• MD, McGill University, 1994-1999.

Research Interests
The ability to develop and maintain a population of memory cells after an infection or vaccination is a sign of adaptive response and the basis of preventive vaccination against infectious pathogens. Understanding the mechanisms implicated in the differentiation of CD8+ T-lymphocytes is therefore essential for improving immunological memory after vaccination and developing novel cell therapy approaches for the treatment of chronic viral infections and cancer. For this reason, our research interests focus, on the one hand, on the study of cell factors that are essential for eliminating a viral pathogen or a tumoral antigen and, on the other hand, on generating and maintaining antigen-specific memory CD8+ T-lymphocytes. By using transgenic mice, we are concentrating in particularly on the role of dependent cytokines of the gamma command chain in the differentiation and generation of memory CD8+ T-lymphocytes after an acute or chronic viral infection or after vaccination. We are also interested in cytotoxic mechanisms that are essential for the effective elimination of viral or tumoral pathogens, especially in immunosuppressed mouse models. Finally, we hope to study the kinetics of the reconstitution and function of anti-viral CD8+ T-lymphocytes after bone marrow transplant.