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DEAL , Cheri  PhD, MD
 
 
     
 
Research Axis
 
   
 
 
 
Research Theme
 
   
 
 
 
Address
 
 
CHU Sainte-Justine
 
 
Centre de recherche
 
 
3175 Chemin de la Côte Sainte-Catherine
 
 
Montréal  (QC), Canada
 
 
H3T 1C5
 
     
 
Phone
 
 
514 345-4931 #6209
 
 
 
 
Fax
 
 
514 345-4988
 
     
     
     

cheri.l.deal@umontreal.ca
 
 
Career Summary, Research Topics and Interests
 

Dr. Deal obtained her PhD (Experimental Medicine), funded by the Medical Research Council of Canada (CIHR), at McGill University, followed by her MD degree at the University of Montreal. She is Canadian and American board certified in Pediatrics (CHU Sainte-Justine/Montreal Children's Hospital) and in Pediatric Endocrinology. She obtained a Medical Research Council Scholarship to pursue a research fellowship in the laboratory of Dr. Ron Rosenfeld at Stanford University in Pediatric Endocrinology from 1989-1991. Dr. Deal has been on staff with the Endocrine Service at CHU Sainte-Justine since 1992, and is tenured Full Professor with the Department of Pediatrics at the University of Montreal as well as an Associate Member of the Faculty of Medicine (Division of Experimental Medicine) of McGill University. Her administrative experience includes the position of past President of the Canadian Pediatric Endocrinology Group (1999-2001), President of the Canadian Society of Endocrinology and Metabolism (2009 – 2011) as well as a member and secretary of the Board of Directors of the Fonds de la recherche en santé du Québec (FRSQ)(1999- 2006). She has served as site leader for the Canadian Institutes of Health Research (C.I.H.R.) Canadian Clinical Scientist Training Program in Pediatrics, and is currently Program Director for Pediatric Endocrinology and Metabolism at the University of Montreal.

Her major research interest is in the contribution of the growth hormone-insulin-like growth factor (GH-IGF) axis to the regulation of human growth. One of her laboratory focuses has been the genetic and epigenetic regulation of IGF2. She received support from the Canadian Breast Cancer Research Initiative to study the role of IGF2 and its receptor in breast cancer. Her secondary field of focus concerns the regulation of various other members of the GH-IGF axis in post-natal life, their role in carcinogenesis, within the context of pre-pubertal obesity, and as a target for clinical intervention in children with Turner Syndrome. Dr. Deal has a strong commitment to patient-driven research, and has helped to elucidate the molecular defects associated with a wide range of rare pediatric endocrine disorders including Type 1 polyglandular autoimmune syndrome (APECED) and congenital hypopituitarism and , as well as participated in clinical studies aimed at ameliorating outcomes in a variety of pediatric endocrine diseases such as congential hypothyroidism, precocious puberty, Prader-Willi syndrome and Turner syndrome. She has over 100 publications.

 
Awards and Distinctions
 
  • Lawson Wilkins Pediatric Endocrine Society Clinical Scholar Award, 1994
  • FRSQ Research Scholarships, 1996, 2001 and 2004

 
Most Important Publications Selected by the Researcher
 
Fillion M, Deal C, Van Vliet G,
Retrospective study of the potential benefits and adverse events during growth hormone treatment in children with Prader-Willi syndrome
J Pediatr 2009  230-233.
 
   
Carel JC, Eugster EA, Rogol A, Ghizzoni L, Palmert MR, Deal C, on behalf the of members of the ESPE-LWPE GnrH analogs consensus conference group,
Consensus statement on the use of GnRH analogs in children
Pediatrics 2009  e752-62.
 
   
Cohen P, Rogol A, Deal C, Saenger P, Reiter EO, Ross JL, Chernausek SD, Savage MO, Wit JM, on behalf of the 2007 ISS Consensus Workshop participants.,
Consensus statement on the diagnosis and treatment of children with idiopathic short stature: a summary of the Growth Hormone Research Society, The Lawson Wilkins Pediatric Endocrine Society and the European Society for Pediatric Endocrinology Workshop
J Clin Endocrinol Metab 2008  4210-4217.
 
   
Abu-Khudir R, Magne F, Chanoine JP, Deal C, Van Vliet G, Deladoëy J,
Role for tissue-dependent methylation differences in the expression of FOXE1 in non-tumoral thyroid glands
J Clin Endocrinol Metab 2014  (sous presse).
 
   
de Kock L, Sabbaghian N, Bouron-Dal Soglio D, Guillerman RP, Park BK, Chami R, Deal C, Priest JR, Foulkes W,
Exploring the association between DICER1 mutations and differentiated thyroid carcinoma
J Clin Endocrinol Metab 2014  (sous presse).
 
   
Publications reported to FRSQ
 
 
 
 
























 
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